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Cenpf cancer

WebNomogram indicated CENPF clinical predictive value for 1-, 3-, 5-, and 7-year melanoma overall survival. Therefore, CENPF plays a vital role in the progression and … WebMar 21, 2024 · The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or …

Overexpression of CENPF correlates with poor prognosis and …

WebFeb 5, 2024 · CENPF/CDK1 signaling pathway enhances the progression of adrenocortical carcinoma by regulating the G2/M-phase cell cycle The result points out that CENPF is significantly overexpressed in ACC patients. The overexpressed CENPF predicts a poor prognosis of ACC and might augment the progress of ACC. WebJan 1, 2024 · CENPF is identified upregulation in pancreatic cancer by genomics profile. • High expression of CENPF is correlated with poor prognosis of patients. • Silencing CENPF significantly inhibited PC cell proliferation, migration and EMT. • Silencing CENPF caused cell cycle arrest and tumorigenicity of pancreatic cells. handbook of media economics volume 1a https://ctmesq.com

CENPF promotes papillary thyroid cancer progression by …

WebBy searching GEO and TCGA database, we found that CENPF was upregulated in breast cancer tissues. Through RT-qPCR, CENPF was found to be upregulated in breast cancer cells. Functional experiments revealed that CENPF had positive effect on the cellular functions, including proliferation, migration and invasion. WebFeb 21, 2024 · As confirmed by the Tumor Immune Estimation Resource, we found highly expressed centromere protein F (CENPF) in SKCM and its metastases. Immunostaining of human melanoma tissues demonstrated high CENPF expression. WebCENPF(KO) cells had reduced global bio-energetic capacity, acetyl-CoA production, histone acetylation, and lipid metabolism, suggesting that CENPF is a critical regulator of cancer … handbook of mathematical formulas

LncRNA MCM3AP-AS1 promotes breast cancer progression via …

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Cenpf cancer

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WebSep 22, 2024 · The expression of CENPF has been detected in different cancers, however its expression pattern differs among various types of cancer. These diverse observations … WebOct 6, 2024 · TOP2A and CENPF are a synergistic pair of MRs that are overexpressed and activated in CC. Their high expression is correlated with some prognosis features (e.g. metastasis) and molecular features (e.g. somatic mutations) and distinctly high in CC vs. many other cancer types. They may be good biomarkers and anticancer drug targets for …

Cenpf cancer

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WebCENPF, CENPE, CENPU, CENPA, and CENPM were the most commonly reported CENPs in breast cancer datasets. Figure 2 The mRNA expression levels of CENPs in different … WebJan 31, 2024 · CENPF has been found to be overexpressed in various malignant tumours, such as prostate cancer, breast cancer, and nasopharyngeal carcinoma, and to activate …

WebFeb 7, 2024 · MiR-1-3p targets CENPF to repress tumor-relevant functions of gastric cancer cells. Zhou S, Han H, Yang L, Lin HZhou S, et al. BMC Gastroenterol, 2024 Mar 28. PMID 35346060 CENPF as an independent prognostic and metastasis biomarker corresponding to CD4+ memory T cells in cutaneous melanoma. WebSep 30, 2024 · Introduction: Hepatocellular carcinoma (HCC) is the most common primary liver cancer with a low 5-year survival rate. The heterogeneity of HCC makes monotherapy unlikely. The development of diagnostic programs and new treatments targeting common genetic events in the carcinogenic process are providing further insights into the …

WebOct 11, 2024 · Overexpression of CENPF correlates with poor prognosis and tumor bone metastasis in breast cancer Abstract. Centromere Protein F (CENPF) associates with the centromere–kinetochore complex and influences cell... Background. Breast cancer (BC) … WebFeb 24, 2024 · Centromere protein F (CENPF), a member of centromere proteins and a transient kinetochore protein, regulates various cellular processes such as cell migration and mitosis, and its upregulation has been observed in multiple types of cancer, including breast cancer and gastric cancer.

WebJan 24, 2024 · Based on these genes, we constructed and validated a 5-gene prognostic signature (including ACADM, CENPF, KDELC1, PLOD2, and TRMT1) to distinguish low- and high-risk KIRC patients of poor survival in TCGA and E-MTAB-1980 cohorts.

WebOct 6, 2024 · Cervical cancer (CC) is the fourth most common female malignancy worldwide. More than half a million women are diagnosed with cervical cancer and the … buses from west malling stationWebFeb 21, 2024 · CENPF was shown to promote the proliferation and migration of HCC cells 16 and accelerate bone metastasis of breast cancer. 21 Additionally, CENPF … handbook of media economicsWebExpression of CENPF (hcp-1) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. ... To access cancer specific RNA and … handbook of meat and meat processingWebApr 10, 2024 · In particular, CENPF overexpression is significantly associated with tumor metastasis and poor prognosis of hepatocellular carcinoma or breast cancer patients [15,16]. In addition, CENPF was also found to be remarkably upregulated in pancreatic cancer, non-small cell lung cancer and papillary thyroid cancer and is commonly … buses from west mersea to colchesterWebFeb 7, 2024 · MiR-1-3p targets CENPF to repress tumor-relevant functions of gastric cancer cells. Zhou S, Han H, Yang L, Lin HZhou S, et al. BMC Gastroenterol, 2024 Mar 28. … handbook of mathematical tables and formulasWebMar 3, 2024 · As one of the biomarkers for CAFs, CENPF can promote the proliferation ability of prostate cancer cells. The overexpress of CENPF could promote the proliferation ability of prostate cancer cells. In conclusion, we discuss the potential prognostic and therapeutic value of CAF-dependent pathways in prostate cancer. Introduction buses from wexham park hospitalWebMar 20, 2024 · Among CENP family genes, CENPF and CENPE are mutated at high frequencies in various tumors, while CENPM and CENPA are less frequently mutated. Furthermore, CENPs regulate the tumor mutational burden, stemness, and microsatellite instability, and are associated with tumor immunity. handbook of mathematics by amit rastogi