WebMay 19, 2011 · In this study the investigators will evaluate the use of biweekly intravenous bevacizumab in combination with five oral drugs (thalidomide, celecoxib, fenofibrate, and alternating cycles of daily low-dose oral etoposide and cyclophosphamide), augmented with alternating courses of intrathecal etoposide and cytarabine. Web30 mg/m 2 intrathecal (IT) q4Days until CSF findings normal plus one additional dose . Refractory Leukemia ... Cardiomyopathy with subsequent death reported following experimental high dose therapy with cytarabine in combination with cyclophosphamide when used for bone marrow transplant preparation.
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WebAug 1, 2024 · Cytarabine Injection, an antineoplastic agent, is a sterile preserved solution for intravenous or subcutaneous administration, and is available in a 500 mg (20 mg per … Webhigh dose therapy with cytarabine and cyclophosphamide therapy when used for bone marrow transplant preparation. This may be schedule dependant. Peripheral motor and sensory neuropathies after consolidation with high dose cytarabine, daunorubicin and … foliage upstate new york
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WebDec 13, 2024 · The most common indirect neurologic complication is chemotherapy-induced peripheral neuropathy (CIPN) ( table 2) [ 1-4 ]. Early recognition of neurotoxicity is important because of potential confusion with metastatic disease, paraneoplastic syndromes, or comorbid neurologic disorders that do not require dose reduction or discontinuation. (See ... Webintrathecal chemotherapy. Materials: Search in PubMed/ Medline using the terms “chemotherapy AND intrathecal”, analysis of secondary and tertiary information sources. Results: e most widely used drugs in intrathecal therapy are methotrexate and cytarabine, at variable doses. WebIntrathecal Use in Meningeal Leukemia: DO NOT USE CYTARABINE INJECTION (which contains benzyl alcohol) INTRATHECALLY. The following dosage information regarding intrathecal use is included for informational purposes only. Cytarabine has been used intrathecally in acute leukemia in doses ranging from 5 mg/m 2 to 75 mg/m 2 of body foliage visibility range